The Quantitative Biology (q-Bio) group is a multidisciplinary team of computer scientists, biologists, mathematicians, and physicists working at the interface of computational modeling and life sciences. Our mission is to develop innovative algorithms and models that integrate biological and medical data to uncover biological mechanisms, support precision medicine, and simulate disease evolution.
Based in the Department of Computer Science at the University of Turin, we are driven by the need to interpret big data in biology and medicine through a systems approach — modeling cancer, genomics, and epidemiology with mathematical rigor and computational innovation, while exploiting high-performance computing (HPC) infrastructures to ensure scalability and efficiency.
Deep Sequencing & Omics Analysis
- Genome assembly, isoform detection, and chimeric RNA discovery and metagenomic analysis.
- CHiP-seq, histone data integration
- Multi-omics integration using AI
- Collaborations with MIRRI & Clinical Sciences for data analisys workflows on HPC infrastrcuture
FAIR Data & Reproducible Research
- Tools like ORCA for reproducible omics data analysis
- Aligned with EU FAIR guidelines
Cancer Modeling & Mechanistic Modeling
- Mathematical modeling of biochemical reactions in cancer
- Differential equation systems for simulating cancer progression
- Patient-specific treatment simulations
- Focus on colorectal, bladder, and cervical cancer
- AI approaches for patients phenomapping.
Longitudinal Data & Functional Analysis
- Functional Data Analysis (FDA) for longitudinal data
- Advanced clustering and trajectory modeling
Cancer Modeling & Mechanistic Modeling
- Mathematical modeling of biochemical reactions in cancer
- Differential equation systems for simulating cancer progression
- Patient-specific treatment simulations
- Focus on colorectal, bladder, and cervical cancer
- AI approaches for patients phenomapping.
We are located on the 1st floor of the Department of Computer Science, in the Center of Piero della Francesca. The center stands on the former industrial area in the nord-west area of Turin. The center hosting the Turin’s high-performance center for artificial intelligence and several companies promoting innovative and fruitful collaborations